Motif ID: STAT5{A,B}.p2

Z-value: 0.890


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT5Achr17_+_404404810.155.8e-01Click!
STAT5Bchr17_-_40428391-0.107.1e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_35168558 3.147 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr20_-_43280359 2.080 NM_000022
ADA
adenosine deaminase
chr20_-_43280249 1.880 ADA
adenosine deaminase
chr19_+_58281049 1.537 ZNF586
zinc finger protein 586
chr19_+_58280996 1.536 NM_001077426
NM_001204814
NM_017652
ZNF586


zinc finger protein 586


chr11_-_82996898 1.243 CCDC90B
coiled-coil domain containing 90B
chr19_+_44669214 1.059 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr11_-_82997376 1.021 NM_021825
CCDC90B
coiled-coil domain containing 90B
chr18_-_53071225 0.942 NM_001243232
TCF4
transcription factor 4
chr1_+_149871154 0.937 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr19_+_35225095 0.891 ZNF181
zinc finger protein 181
chr6_+_84569394 0.875 CYB5R4
cytochrome b5 reductase 4
chr6_+_116601282 0.856 NM_001080976
DSE
dermatan sulfate epimerase
chr22_+_39077960 0.798 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr22_+_39077975 0.777 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr22_+_39077979 0.775 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr19_-_44439410 0.772 NM_003425
ZNF45
zinc finger protein 45
chr6_+_84569364 0.768 NM_016230
CYB5R4
cytochrome b5 reductase 4
chr5_+_178286913 0.754 NM_058230
ZNF354B
zinc finger protein 354B
chr6_-_32784727 0.740 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr22_+_39077953 0.729 NM_020243
TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr14_+_65877309 0.727 NM_004480
NM_178155
NM_178156
FUT8


fucosyltransferase 8 (alpha (1,6) fucosyltransferase)


chr6_-_159240367 0.724 EZR
ezrin
chr1_-_31230673 0.714 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr6_-_159240398 0.700 EZR
ezrin
chr6_+_84569427 0.681 CYB5R4
cytochrome b5 reductase 4
chr6_-_159240399 0.669 EZR
ezrin
chr6_-_27440459 0.623 NM_007149
ZNF184
zinc finger protein 184
chr12_+_133656984 0.619 NM_003440
ZNF140
zinc finger protein 140
chr1_-_221910801 0.618 NM_144728
DUSP10
dual specificity phosphatase 10
chr1_-_203154304 0.611 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_-_132766834 0.600 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_159240433 0.591 NM_001111077
EZR
ezrin
chr19_+_44716683 0.550 NM_182490
ZNF227
zinc finger protein 227
chr9_+_112542496 0.545 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr19_+_35225479 0.529 NM_001029997
NM_001145665
ZNF181

zinc finger protein 181

chr12_+_133657478 0.522 ZNF140
zinc finger protein 140
chrX_-_154563735 0.480 NM_001289
CLIC2
chloride intracellular channel 2
chr1_-_33502484 0.479 NM_001199199
NM_001625
NM_013411
AK2


adenylate kinase 2


chr17_-_5322982 0.477 NM_002532
NUP88
nucleoporin 88kDa
chr2_-_231084600 0.471 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr14_+_24630421 0.466 NM_006084
IRF9
interferon regulatory factor 9
chr12_+_133657439 0.457 ZNF140
zinc finger protein 140
chr22_+_50624267 0.428 TRABD
TraB domain containing
chr10_+_124913884 0.420 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr20_+_34556528 0.418 NM_001207076
NM_080834
C20orf152

chromosome 20 open reading frame 152

chr15_-_83736105 0.417 NM_001011885
NM_025238
BTBD1

BTB (POZ) domain containing 1

chr19_+_44507076 0.417 NM_006300
ZNF230
zinc finger protein 230
chr15_+_75315931 0.413 PPCDC
phosphopantothenoylcysteine decarboxylase
chr22_+_50624353 0.394 NM_025204
TRABD
TraB domain containing
chr15_+_42066631 0.371 NM_001128608
NM_014994
MAPKBP1

mitogen-activated protein kinase binding protein 1

chr15_+_75315926 0.370 NM_021823
PPCDC
phosphopantothenoylcysteine decarboxylase
chr1_-_54518915 0.367 TMEM59
transmembrane protein 59
chr1_-_54518790 0.363 TMEM59
transmembrane protein 59
chr1_-_54518886 0.360 TMEM59
transmembrane protein 59
chr15_+_42066690 0.348 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr19_-_58427934 0.347 NM_152475
ZNF417
zinc finger protein 417
chr1_+_38478366 0.347 NM_016037
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr15_-_83735892 0.345 BTBD1
BTB (POZ) domain containing 1
chrX_+_48334400 0.340 NM_012280
NM_177439
FTSJ1

FtsJ homolog 1 (E. coli)

chr19_+_17378264 0.335 BABAM1
BRISC and BRCA1 A complex member 1
chr20_-_18477811 0.328 NM_006606
RBBP9
retinoblastoma binding protein 9
chr5_-_111093251 0.320 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr11_+_86013252 0.313 NM_016401
C11orf73
chromosome 11 open reading frame 73
chr1_+_38478408 0.312 UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr6_+_139094656 0.312 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr12_-_46384346 0.309 SCAF11
SR-related CTD-associated factor 11
chr12_-_46384365 0.308 NM_004719
SCAF11
SR-related CTD-associated factor 11
chr1_-_31230594 0.304 LAPTM5
lysosomal protein transmembrane 5
chr19_-_50528683 0.301 NM_001025778
NM_016440
VRK3

vaccinia related kinase 3

chr19_+_44576266 0.293 NM_001037813
ZNF284
zinc finger protein 284
chrX_-_154250769 0.290 NM_000132
F8
coagulation factor VIII, procoagulant component
chr5_+_85913755 0.287 COX7C
cytochrome c oxidase subunit VIIc
chr19_-_37019169 0.279 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr4_+_86396251 0.275 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr5_+_61602065 0.275 KIF2A
kinesin heavy chain member 2A
chr22_-_38902344 0.267 NM_001098504
NM_006386
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr19_-_45004482 0.265 NM_013256
ZNF180
zinc finger protein 180
chr7_-_132766697 0.263 NM_017812
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr17_-_5322870 0.261 NUP88
nucleoporin 88kDa
chr2_+_44001177 0.241 NM_001193464
NM_015522
NM_016008
DYNC2LI1


dynein, cytoplasmic 2, light intermediate chain 1


chrX_+_107288199 0.234 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr19_-_58514136 0.233 ZNF606
zinc finger protein 606
chr15_+_91643181 0.231 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr11_+_134123406 0.224 NM_014384
ACAD8
acyl-CoA dehydrogenase family, member 8
chr19_+_58144510 0.218 NM_006385
NM_198855
ZNF211

zinc finger protein 211

chr19_+_17378148 0.215 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1

chr19_+_44488331 0.215 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr1_-_160617042 0.208 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr1_-_33502428 0.207 AK2
adenylate kinase 2
chr4_+_174292100 0.206 SAP30
Sin3A-associated protein, 30kDa
chr18_+_72163335 0.205 NM_018235
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr3_+_180319898 0.201 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr4_+_174292027 0.201 NM_003864
SAP30
Sin3A-associated protein, 30kDa
chrX_+_47050208 0.200 UBA1
ubiquitin-like modifier activating enzyme 1
chr22_-_38902300 0.197 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr11_-_134123138 0.186 NM_001037304
NM_001037305
NM_014174
NM_199297
NM_199298
THYN1




thymocyte nuclear protein 1




chr18_-_43684198 0.183 NM_001001937
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr7_+_99102272 0.182 NM_145102
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr3_+_197677049 0.181 NM_000996
RPL35A
ribosomal protein L35a
chr19_+_50529294 0.180 ZNF473
zinc finger protein 473
chr22_-_38902281 0.179 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr9_-_134955243 0.178 NM_004269
CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27
chr9_+_15422875 0.177 SNAPC3
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr9_+_130186652 0.177 NM_007135
ZNF79
zinc finger protein 79
chr16_+_53468362 0.175 RBL2
retinoblastoma-like 2 (p130)
chr14_-_82000112 0.172 SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr9_+_15422862 0.172 SNAPC3
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr14_-_82000198 0.172 NM_001244984
NM_005065
SEL1L

sel-1 suppressor of lin-12-like (C. elegans)

chr16_-_70472920 0.170 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr5_+_85913762 0.170 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr3_+_14166439 0.170 NM_024334
TMEM43
transmembrane protein 43
chr9_+_15422630 0.167 NM_001039697
SNAPC3
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr15_+_91643429 0.166 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr1_-_33502470 0.165 AK2
adenylate kinase 2
chr1_-_27961623 0.164 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr11_+_114167168 0.163 NNMT
nicotinamide N-methyltransferase
chr8_-_66546394 0.160 ARMC1
armadillo repeat containing 1
chr3_+_196466806 0.159 PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr19_-_50528627 0.154 VRK3
vaccinia related kinase 3
chr7_+_142960588 0.149 GSTK1
glutathione S-transferase kappa 1
chrX_+_47050091 0.145 NM_153280
UBA1
ubiquitin-like modifier activating enzyme 1
chr19_+_44529493 0.144 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr18_-_44561967 0.143 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr8_-_101965601 0.142 NM_003406
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr19_-_48018317 0.141 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr16_+_53468390 0.140 RBL2
retinoblastoma-like 2 (p130)
chr15_+_66874506 0.136


chr15_-_83953465 0.134 NM_001717
BNC1
basonuclin 1
chr3_+_130745693 0.128 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr16_+_53468344 0.127 NM_005611
RBL2
retinoblastoma-like 2 (p130)
chr7_+_99102601 0.127 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr5_+_140753480 0.126 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr10_-_103815868 0.126 NM_024541
C10orf76
chromosome 10 open reading frame 76
chr12_-_117747214 0.124 NM_001204214
NOS1
nitric oxide synthase 1 (neuronal)
chr1_+_53392957 0.121 SCP2
sterol carrier protein 2
chrX_-_48931645 0.121 NM_007213
PRAF2
PRA1 domain family, member 2
chr3_+_14166543 0.120 TMEM43
transmembrane protein 43
chr6_-_116601085 0.118 TSPYL1
TSPY-like 1
chr12_+_21284127 0.118 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr14_+_97263681 0.116 NM_003384
VRK1
vaccinia related kinase 1
chr7_+_128502926 0.115 ATP6V1F
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr3_+_183892569 0.115 NM_001025205
NM_004068
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr15_+_48624354 0.113 NM_001948
DUT
deoxyuridine triphosphatase
chr8_-_101965554 0.113 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_-_217540722 0.113 IGFBP5
insulin-like growth factor binding protein 5
chr14_+_68286495 0.112 NM_002877
NM_133509
NM_133510
RAD51B


RAD51 homolog B (S. cerevisiae)


chr11_+_2920910 0.111 NM_183233
SLC22A18
solute carrier family 22, member 18
chr1_+_155108276 0.111 NM_001122837
NM_001122839
NM_018845
SLC50A1


solute carrier family 50 (sugar transporter), member 1


chr19_-_47354060 0.110 NM_004069
NM_021575
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr3_-_197463713 0.110 NM_014687
KIAA0226
KIAA0226
chr7_+_2598712 0.110 IQCE
IQ motif containing E
chr2_+_63816143 0.107 NM_001199111
NM_001199112
MDH1

malate dehydrogenase 1, NAD (soluble)

chr1_-_33502452 0.104 AK2
adenylate kinase 2
chr13_-_52378230 0.104 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr7_+_99102572 0.103 NM_014569
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr7_-_108096693 0.101 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr2_+_63816092 0.099 MDH1
malate dehydrogenase 1, NAD (soluble)
chr3_+_14166582 0.097 TMEM43
transmembrane protein 43
chr6_-_166582129 0.097 NM_003181
T
T, brachyury homolog (mouse)
chr14_-_77923888 0.095 NM_001193314
NM_001193315
NM_001193316
NM_001193317
NM_022067
C14orf133




chromosome 14 open reading frame 133




chr16_+_15596122 0.094 NM_001142469
C16orf45
chromosome 16 open reading frame 45
chr19_-_58951588 0.094 NM_003433
ZNF132
zinc finger protein 132
chr14_+_77787229 0.094 NM_145870
NM_145871
GSTZ1

glutathione transferase zeta 1

chr1_+_155108343 0.093 SLC50A1
solute carrier family 50 (sugar transporter), member 1
chr1_+_53392900 0.091 NM_001007098
NM_001193599
NM_001193600
NM_001193617
NM_002979
SCP2




sterol carrier protein 2




chr3_+_183892699 0.090 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_+_58987751 0.090 NM_017908
ZNF446
zinc finger protein 446
chr12_-_10324675 0.086 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr19_+_58095507 0.086 NM_001010879
ZIK1
zinc finger protein interacting with K protein 1 homolog (mouse)
chr16_-_20338808 0.085 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr7_-_150754934 0.085 CDK5
cyclin-dependent kinase 5
chr19_+_39390570 0.085 NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr7_+_142985307 0.084 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr3_+_183892662 0.083 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_-_49449106 0.082 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr1_-_54519050 0.081 NM_004872
TMEM59
transmembrane protein 59
chr11_+_16760147 0.081 NM_014267
C11orf58
chromosome 11 open reading frame 58
chr16_+_53468373 0.081 RBL2
retinoblastoma-like 2 (p130)
chr7_+_128502856 0.080 NM_001198909
NM_004231
ATP6V1F

ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F

chr15_+_22833394 0.079 NM_001102610
NM_052903
TUBGCP5

tubulin, gamma complex associated protein 5

chr19_-_57183122 0.078 NM_001005850
ZNF835
zinc finger protein 835
chr16_-_30103204 0.077 NM_004608
TBX6
T-box 6
chr19_+_36209125 0.076 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr3_+_183892668 0.075 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr2_+_172290796 0.075 DCAF17
DDB1 and CUL4 associated factor 17
chr2_+_74740585 0.075 TLX2
T-cell leukemia homeobox 2
chr11_+_67374322 0.075 NM_001166102
NM_007103
NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

chr22_-_38902315 0.074 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr8_-_66546413 0.073 NM_018120
ARMC1
armadillo repeat containing 1
chr16_+_67204404 0.070 NM_001185058
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr17_+_15603046 0.069 ZNF286A
zinc finger protein 286A
chr17_-_39538635 0.068 NM_021013
KRT34
keratin 34
chr3_+_183892647 0.068 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr7_-_48019115 0.067 HUS1
HUS1 checkpoint homolog (S. pombe)
chr6_+_36410543 0.066 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr16_+_53738044 0.066 FTO
fat mass and obesity associated
chr2_-_68290114 0.066 C1D
C1D nuclear receptor corepressor
chr2_-_241500459 0.065 ANKMY1
ankyrin repeat and MYND domain containing 1
chr19_+_58341661 0.065 NM_001204818
LOC100293516
zinc finger protein

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
6.10 5.96e-03 GO:0008270 zinc ion binding
5.25 1.09e-02 GO:0046914 transition metal ion binding